SynTumor Cancer-on-a-Chip
Real-time monitoring of cell-cell interactions between tumor, stromal, vascular, and immune cells on Chip
SynTumor Idealized Linear Chip Schematic
SynTumor Idealized Radial Chip Schematic
SynTumor Microvascular Network Chip Schematic
SynTumor™ Cancer-on-a-Chip is an advanced 3D tumor modeling platform that offers real-time visualization and quantitative analysis of cell-cell and cell-drug interactions within a realistic tumor microenvironments. The models are built on idealized or simulated vascular networks and also include interstitial and/or tumor space designed to replicate physiologically and morphologically accurate structures. The models simulate dynamic processes such as blood circulation, transport across vessel walls, and targeted delivery to tumors providing a comprehensive and realistic simulation of the tumor microenvironment.
Co-Culture Chips
Microvascular networks recapitulate in vivo scale and vascular geometry. Idealized Network
Multi-Chamber Chips
Low or High Perfusion
Tandem Co-Culture, Multi-Chamber Chips
Designed with Separate Vascular Network Beds
Applications and Assays
Publications Using SynTumor Models
Contract Research Services using SynTumor models
Drug delivery under physiological flow, safety, efficacy, metastasis, CAR-T cytotoxicity, multi-organ modeling and more
SynTumor Models Available
Monoculture using tumor cells/cell lines- Human or rodent
Co-Culture with tumor cells and matched endothelial cells
Tri-Culture with tumor, stromal and endothelial cells
Blood Brain Tumor Barrier Model-Primary or iPSC-derived cells
- Brain endothelial cells, astrocytes, pericytes and tumor cells and CAR-T tracking for cytotoxicity or neurotoxicity
Incorporate immune cells in any model
Assays Available
Efficacy and toxicity screening
Cell proliferation, morphology, and viability
Tumor-induced vascular leakage
Tumor intravasation and extravasation
Tumor immune cell interactions
Drug delivery, uptake, and efficacy
Biomarker analysis
On-chip or off-chip analysis
Brochures and Technical Manuals
Videos
Purchase SynTumor Products and Instruments
Purchase starter kits, sets of chips, instrumentation and training workshops
SynTumor Starter Kit: Select this for your first-time purchase. All the basic components required to run SynTumor assays can be purchased in a kit format. The SynTumor starter kit includes 12 chips, tubing, clamps, needles, syringes, pneumatic priming device (required for seeding cells).
SynTumor Chip Options: Depending on your specific research applications you can select from Linear, Radial or Microvascular configurations.
Instrumentation: Syringe Pumps for cell seeding and maintaining flow based assays, stage top Incubator and inverted microscope for real time visualization and quantitation of your Tumor assays
Training Workshops: SynVivo offers 2 and 4 day scientist-led training sessions. Gain hands on experience with our organ-on-a-chip technology.
Starter Kits - Select your chip model
Important Note: Starter kit does not include required consumables such as cells, media, and matrix. Other required equipment not included is syringe pumps, cell seeding pumps, incubators, and microscopes.
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Chip Model | CAT# | Product Name | Price | Qty | |
|---|---|---|---|---|---|
 | 403002 | $2,100 | |||
| 403006 | $2,100 | |||
 | 403004 | $2,500 | |||
| 403008 | $2,500 | |||
 | 403012 | $2,100 | |||
| 403010 | $2,100 |
SynTumor Model Chips
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Chip Model | CAT# | Product Name | Price | Qty | |
|---|---|---|---|---|---|
| 102004-STu3 | $375 | |||
| 102012-STu3 | $375 | |||
| 108007-STu3 | $375 | |||
| 108011-STu3 | $375 | |||
| 105007-STu3 | $499 | |||
| 105015-STu3 | $499 | |||
 | 106009-3 | $575 | |||
 | 106010-3 | $575 | |||
 | 106013-3 | $575 |
Training Workshops
Syringe Pumps - Instrumentation for Seeding Cells and Maintaining Flow Based Assays
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Image | CAT# | Product Name | Price | Qty | |
|---|---|---|---|---|---|
 | 301004 | PHD Ultra 6/10 Multi Syringe Rack | $920 | ||
 | 301020 | Multichannel Programmable Syringe Pump – SynVivo NE 1200 | $2,100 | ||
 | 301002 | Pump 11 Elite Nanomite Infusion/Withdrawal Programmable Single Syringe | $3,790 | ||
 | 301003 | PHD Ultra Syringe Pump Programmable 2-Syringe Rack Standard Pressure | $5,651 |
Tokai Hit Stage Top Incubators
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Image | CAT# | Product Name | Contact Us |
|---|---|---|---|
 | 303015 | ||
| 303016 | ||
| 303017 |