3D Tissue and Organ-On-Chip Models

synvivo synbbb

SynBBB

Neuroscience
synvivo synram

SynRAM

Inflammation
SynTumor -Endothelial Interactions

SynTumor

Oncology
synvivo synali alveolar lung model

SynALI

Air Liquid Interface
synvivo syntox 10x co-culture

SynTox

Toxicology
chip 250

Microfluidic Chips

stagetop3

Instruments

synvivo-kit

Accessories

About SynVivo

SynVivo is a cell-based microfluidic organ-on-chip platform that provides a biologically realistic microenvironment for the real-time study of cellular behavior, drug delivery, and drug discovery. This proprietary technology links the high-tech domains of microfluidics and bioengineering for broad applications in the life science arena. SynVivo proprietary microfluidic chips are capable of supporting a microvascular network that simulates the circulation inside any tissue with respect to flow, shear, and pressure. Human cells grown in SynVivo chips retain biological phenotypes that are similar to cells found in the tissues. Scientific research and publications have validated that cells grown in SynVivo chips more accurately reflect the tissue cells found inside the body than do cells grown using conventional culture techniques.

SynVivo chips have the potential to be a game-changer for diseases because they enable the use of cells from patient biopsies to replicate the tumor environment for testing the efficacy of drugs or drug combinations—thus providing a novel personalized medicine approach to cancer therapy.

Real time Visualization and Quantitation of Cell-Cell and Cell-Drug Interactions

Unlike well plate testing performed under static conditions, SynVivo reproduces the realistic dynamic conditions for analyzing cell-drug and cell-cell interactions thereby providing an accurate in vitro platform to study and elucidate the mechanisms of success and failure. Compared to in vivo animal studies, SynVivo allows real-time visualization and analysis of the assay in a controlled environment. The ability to culture human cells in SynVivo brings the assay that much closer to the intended clinical use.

Screening, Assay and Model Development Services

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