Category Archives: Publications

PKCδ Inhibition as a Novel Medical Countermeasure for Radiation‐Induced Vascular Damage

Authors: Fariborz Soroush, Yuan Tang, Hasan M. Zaidi, Joel B. Sheffield, Laurie E. Kilpatrick, Mohammad F. Kiani Source: faseb.onlinelibrary.wiley.com First published: 13 June 2018 Synopsis: In the event of a…

Rational Design and Development of a Peptide Inhibitor for the PD-1/ PD-L1 Interaction

Authors: Rebecca J. Boohaker, Vijaya Sambandam, Isaac Segura, James Miller, Mark Suto, Bo Xu Source: journals.elsevier.com Received February 10, 2018. Received in revised form April 13, 2018. Accepted April 22,…

A Microvascularized Tumor-mimetic Platform for Assessing Anti-cancer Drug Efficacy

Authors: Shantanu Pradhan, Ashley M. Smith, Charles J. Garson, Iman Hassani, Wen J. Seeto, Kapil Pant, Robert D. Arnold, Balabhaskar Prabhakarpandian & Elizabeth A. Lipke Source: nature.com Scientific Reports volume…

Microfluidic Co-Culture Devices to Assess Penetration of Nanoparticles into Cancer Cell Mass

Authors: Maria Jarvis, Michael Arnold, Jenna Ott, Kapil Pant, Balabhaskar Prabhakarpandian, Samir Mitragotri Source: pubmed.ncbi.nlm.nih.gov Bioeng Transl Med. 2017 Sep 26;2(3):268-277. doi: 10.1002/btm2.10079. eCollection 2017 Sep. Synopsis: In vitro and…

Murine Glomerular Transcriptome Links Endothelial Cell-Specific Molecule-1 Deficiency with Susceptibility to Diabetic Nephropathy

Authors: Xiaoyi Zheng, Fariborz Soroush, Jin Long, Evan T. Hall, Puneeth K. Adishesha, Sanchita Bhattacharya, Mohammad F. Kiani, Vivek Bhalla Source: ncbi.nlm.nih.gov Received: April 18, 2017. Accepted: September 8, 2017.…

A Biomimetic Microfluidic Tumor Microenvironment Platform Mimicking the EPR Effect for Rapid Screening of Drug Delivery Systems

Authors: Yuan Tang, Fariborz Soroush, Joel B. Sheffield, Bin Wang, Balabhaskar Prabhakarpandian & Mohammad F. Kiani Source: nature.com Scientific Reports volume 7, Article number: 9359 (2017) Synopsis: Real-time monitoring of…

Trastuzumab Distribution in an In-Vivo and In-Vitro Model of Brain Metastases of Breast Cancer

Authors: Tori B. Terrell-Hall, Mohamed Ismail Nounou, Fatema El-Amrawy, Jessica I.G. Griffith, and Paul R. Lockman Source: oncotarget.com Oncotarget. 2017; 8:83734-83744. Received: March 15, 2017. Accepted: July 03, 2017. Published: July 26,…

Permeability Across a Novel Microfluidic Blood-Tumor Barrier Model

Authors: Tori B. Terrell-Hall, Amanda G. Ammer, Jessica I. G. Griffith, and Paul R. Lockman Source: ncbi.nlm.nih.gov Fluids Barriers CNS. 2017; 14: 3. Published online 2017 Jan 23. doi: 10.1186/s12987-017-0050-9…

A Novel Microfluidic Assay Reveals a Key Role for Protein Kinase C δ in Regulating Human Neutrophil-Endothelium Interaction

Authors: Fariborz Soroush, Ting Zhang, Devon J King, Yuan Tang, Sudhir Deosarkar, Balabhaskar Prabhakarpandian, Laurie E Kilpatrick, Mohammad F Kiani Source: pubmed.ncbi.nlm.nih.gov J Leukoc Biol. 2016 Nov;100(5):1027-1035. doi: 10.1189/jlb.3MA0216-087R. Epub…

A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip

Authors: Sudhir P. Deosarkar, Balabhaskar Prabhakarpandian, Bin Wang, Joel B. Sheffield, Barbara Krynska, Mohammad F. Kiani Source: journals.plos.org Published: November 10, 2015 Synopsis: Studies of neonatal neural pathologies and development…