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SynVivo
3D Tissue and Organ-on-Chip Models
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    • 3D Tissue & Organ on Chip
      • SynBBB 3D Blood Brain Barrier Model
      • SynRAM 3D Inflammation Model
      • SynTumor 3D Cancer Model​
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      • SynTox 3D Toxicology Model
    • Microfluidic Chips
      • Linear Channels
      • Bifurcating Channels
      • Microvascular Networks
      • Idealized Networks
    • Instruments
      • Pneumatic Primer
      • Cell Impedance Analyzer
      • Syringe pumps
      • Stage Top Incubators
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Category Archives: Publications

JCBFM

Characterization of human fetal brain endothelial cells reveals barrier properties suitable for in vitro modeling of the BBB with syngenic co-cultures

PublicationsBy Gwen FewellOctober 20, 2018

Authors: Allison M Andrews, Evan M Lutton, Lee A Cannella, Nancy Reichenbach, Roshanak Razmpour, Matthew J Seasock, Steven J Kaspin, Steven F Merkel, Dianne Langford, Yuri Persidsky and Servio H…

small journal

Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization‐Induced Self‐Assembly

PublicationsBy Gwen FewellJuly 25, 2018

Authors: Song Yang Khor, Mai N. Vu, Emily H. Pilkington, Angus P. R. Johnston, Michael R. Whittaker, John F. Quinn, Nghia P. Truong, Thomas P. Davis Source: onlinelibrary.wiley.com First published:…

faseb journal

PKCδ Inhibition as a Novel Medical Countermeasure for Radiation‐Induced Vascular Damage

PublicationsBy Gwen FewellJune 13, 2018

Authors: Fariborz Soroush, Yuan Tang, Hasan M. Zaidi, Joel B. Sheffield, Laurie E. Kilpatrick, Mohammad F. Kiani Source: faseb.onlinelibrary.wiley.com First published: 13 June 2018 Synopsis: In the event of a…

cancer letters journal

Rational Design and Development of a Peptide Inhibitor for the PD-1/ PD-L1 Interaction

PublicationsBy Gwen FewellApril 22, 2018

Authors: Rebecca J. Boohaker, Vijaya Sambandam, Isaac Segura, James Miller, Mark Suto, Bo Xu Source: journals.elsevier.com Received February 10, 2018. Received in revised form April 13, 2018. Accepted April 22,…

scientific reports journal

A Microvascularized Tumor-mimetic Platform for Assessing Anti-cancer Drug Efficacy

PublicationsBy Gwen FewellFebruary 16, 2018

Authors: Shantanu Pradhan, Ashley M. Smith, Charles J. Garson, Iman Hassani, Wen J. Seeto, Kapil Pant, Robert D. Arnold, Balabhaskar Prabhakarpandian & Elizabeth A. Lipke Source: nature.com Scientific Reports volume…

bioengineering translational medicine

Microfluidic Co-Culture Devices to Assess Penetration of Nanoparticles into Cancer Cell Mass

PublicationsBy Gwen FewellSeptember 26, 2017

Authors: Maria Jarvis, Michael Arnold, Jenna Ott, Kapil Pant, Balabhaskar Prabhakarpandian, Samir Mitragotri Source: pubmed.ncbi.nlm.nih.gov Bioeng Transl Med. 2017 Sep 26;2(3):268-277. doi: 10.1002/btm2.10079. eCollection 2017 Sep. Synopsis: In vitro and…

plos one

Murine Glomerular Transcriptome Links Endothelial Cell-Specific Molecule-1 Deficiency with Susceptibility to Diabetic Nephropathy

PublicationsBy Gwen FewellSeptember 21, 2017

Authors: Xiaoyi Zheng, Fariborz Soroush, Jin Long, Evan T. Hall, Puneeth K. Adishesha, Sanchita Bhattacharya, Mohammad F. Kiani, Vivek Bhalla Source: ncbi.nlm.nih.gov Received: April 18, 2017. Accepted: September 8, 2017.…

A Biomimetic Microfluidic Tumor Microenvironment Platform Mimicking the EPR Effect for Rapid Screening of Drug Delivery Systems

PublicationsBy Gwen FewellAugust 24, 2017

Authors: Yuan Tang, Fariborz Soroush, Joel B. Sheffield, Bin Wang, Balabhaskar Prabhakarpandian & Mohammad F. Kiani Source: nature.com Scientific Reports volume 7, Article number: 9359 (2017) Synopsis: Real-time monitoring of…

oncotarget journal

Trastuzumab Distribution in an In-Vivo and In-Vitro Model of Brain Metastases of Breast Cancer

PublicationsBy Gwen FewellJuly 26, 2017

Authors: Tori B. Terrell-Hall, Mohamed Ismail Nounou, Fatema El-Amrawy, Jessica I.G. Griffith, and Paul R. Lockman Source: oncotarget.com Oncotarget. 2017; 8:83734-83744. Received: March 15, 2017. Accepted: July 03, 2017. Published: July 26,…

Fluids-and-barriers

Permeability Across a Novel Microfluidic Blood-Tumor Barrier Model

PublicationsBy Gwen FewellJanuary 23, 2017

Authors: Tori B. Terrell-Hall, Amanda G. Ammer, Jessica I. G. Griffith, and Paul R. Lockman Source: ncbi.nlm.nih.gov Fluids Barriers CNS. 2017; 14: 3. Published online 2017 Jan 23. doi: 10.1186/s12987-017-0050-9…

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