Category Archives: Publications

Experimental Approaches to Evaluate Leukocyte-Endothelial Cell Interactions in Sepsis and Inflammation

Authors: Kilpatrick, Laurie E.; Kiani, Mohammad F. SHOCK: May 2020 – Volume 53 – Issue 5 – p 585-595 doi: 10.1097/SHK.0000000000001407 Synopsis: Sepsis is a life-threatening syndrome of organ dysfunction…

Neutrophil‐endothelial interactions of murine cells is not a good predictor of their interactions in human cells

Authors: Fariborz Soroush, Yuan Tang, Omar Mustafa, Shuang Sun, Qingliang Yang, Laurie E. Kilpatrick, Mohammad F. Kiani Synopsis: All drugs recently developed in rodent models to treat inflammatory disease have…

Reversible Cavitation-Induced Junctional Opening in an Artificial Endothelial Layer

Authors: Giulia Silvani, Chiara Scognamiglio, Davide Caprini, Luca Marino, Mauro Chinappi, Giorgia Sinibaldi, Giovanna Peruzzi, Mohammad F. Kiani, and Carlo M. Casciola Source: onlinelibrary.wiley.com Advance Science News, Small Journal Received:…

Co-Cultured Microfluidic Model Of The Airway Optimized For Microscopy And Micro-Optical Coherence Tomography Imaging

Authors: Zhongyu Liu, Stephen Mackay, Dylan M. Gordon, Justin D. Anderson, Dustin W. Haithcock, Charles J. Garson, Guillermo J. Tearney, George M. Solomon, Kapil Pant, Balabhaskar Prabhakarpandian, Steven M. Rowe,…

Size, shape, and flexibility influence nanoparticle transport across brain endothelium under flow

Authors: Maxsymilian Nowak, Tyler Brown, Adam Graham, Matthew Helgeson and Samir Mitragotri Source: Bioengineering and Translational Medicine Published online: September 20, 2019. Synopsis: Nanoparticle-based therapeutic formulations are being increasingly explored for…

Shape Effect In Active Targeting Of Nanoparticles To Inflamed Cerebral Endothelium Under Static And Flow Conditions

Authors: A. Da Silva-Candal, T. Brown, V. Krishnan, I. Lopez-Loureiro, P. Ávila-Gómez, A.Pusuluri, A. Pérez-Díaz, C. Correa-Paz, P. Hervella, J. Castillo, S. Mitragotri, F. Campos Source: sciencedirect.com Journal of Controlled…

Rapid Assessment of Nanoparticle Extravasation in a Microfluidic Tumor Model

Authors: Mai N. Vu, Pradeep Rajasekhar, Daniel P. Poole, Song Yang Khor, Nghia P. Truong, Cameron J. Nowell, John F. Quinn, Michael Whittaker, Nicholas A. Veldhuis, and Thomas P. Davis…

The Role of Tyrosine Phosphorylation of Protein Kinase C Delta in Infection and Inflammation

Authors: Qingliang Yang, Jordan C. Langston, Yuan Tang, Mohammad F. Kiani, and Laurie E. Kilpatrick Source: ncbi.nlm.nih.gov Int J Mol Sci. 2019 Mar; 20(6): 1498. Published online 2019 Mar 26.…

A Microfluidic Model Of Human Brain (uHuB) For Assessment of Blood Brain Barrier

Authors: Tyler D. Brown, Maksymilian Nowak, Alexandra V. Bayles, Balabhaskar Prabhakarpandian, Pankaj Karande, Joerg Lahann, Matthew E. Helgeson, Samir Mitragotri Source: onlinelibrary.wiley.com WILEY AIChE, Bioengineering and Translational Medicine Received: 7…

Protein Kinase C-Delta Inhibition Protects Blood-Brain Barrier From Sepsis-Induced Vascular Damage

Authors: Yuan Tang, Fariborz Soroush, Shuang Sun, Elisabetta Liverani, Jordan C. Langston, Qingliang Yang, Laurie E. Kilpatrick, and Mohammad F. Kiani Source: ncbi.nlm.nih.gov Tang et al. Journal of Neuroinflammation (2018)…