A nanopolymer used for drug delivery was complexed with GFP DNA and perfused on tumor cell (HeLa) cultured networks. GFP transfection, efficiencies and distribution was quantified at 24 hours post injection.
HeLa Cells Transfection with GFP Gene
SynVivo can support the growth of tumor cells and drug delivery and efficacy can be studied. The effect of in vivo morphology and fluidic conditions on transfection can be quantified so that the delivery vehicle can be optimized.